2,6-dimethyl-4-hydroxy pyridine
2,6-dimethyl-4-hydroxy pyridine
CAS: 13603-44-6
Molecular Formula: C7H9NO
2,6-dimethyl-4-hydroxy pyridine - Names and Identifiers
| Name | 2,6-dimethyl-4-hydroxy pyridine |
| Synonyms | 2,6-Dimethyl-4-pyridinol 2,6-Dimethylpyridine-4-ol 2,6-DIMETHYL-PYRIDIN-4-OL 2,6-dimethylpyridin-4(1H)-one 2,6-DIMETHYL-4-HYDROXYPYRIDINE 4-HYDROXY-2,6-DIMETHYLPYRIDINE 2,6-Dimethyl-4-hydroxypyridine 4-Hydroxy-2,6-dimethylpyridine 2,6-dimethyl-4-hydroxy pyridine 2,6-Dimethylpyridin-4-ol, 4-Hydroxy-2,6-lutidine |
| CAS | 13603-44-6 |
| EINECS | 237-089-2 |
| InChI | InChI=1/C7H9NO/c1-5-3-7(9)4-6(2)8-5/h3-4H,1-2H3,(H,8,9) |
| InChIKey | PRAFLUMTYHBEHE-UHFFFAOYSA-N |
2,6-dimethyl-4-hydroxy pyridine - Physico-chemical Properties
| Molecular Formula | C7H9NO |
| Molar Mass | 123.15 |
| Density | 1,053g/cm |
| Melting Point | 230-232°C |
| Boling Point | 351 °C |
| Flash Point | 93.1°C |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| Vapor Presure | 0.251mmHg at 25°C |
| Appearance | Yellow to brown crystals |
| Color | White to Off-White |
| pKa | 5.49±0.23(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1,501-1,503 |
| MDL | MFCD00956021 |
2,6-dimethyl-4-hydroxy pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
2,6-dimethyl-4-hydroxy pyridine - Introduction
2,6-dimethyl-4-hydroxypyridine (abbreviated as DMHP) is an organic compound whose chemical formula is C9H11NO. The following is a description of the nature, use, preparation and safety information of DMHP:
1. nature:
- DMHP is a solid, usually in the form of white crystals or crystalline powder.
-It is soluble in many organic solvents at room temperature, such as ethanol, ether and dichloromethane.
- DMHP is stable in air, but may decompose under the action of high temperature, high pressure or strong oxidants.
-It is an alkaline substance that can react with acid to generate the corresponding salt.
2. use:
- DMHP is often used as a catalyst in organic synthesis reactions, especially in the synthesis of carbonyl compounds.
-It can be used as a condensing agent for the synthesis of aromatic aldehydes and ketones.
- DMHP can also be used to synthesize biologically active compounds, such as drugs and natural products.
3. Preparation method:
The synthesis of-DMHP is usually achieved by introducing methyl and hydroxyl groups at the 2 and 6 positions of pyridine. Specific methods include oxidation, alkylation, aldehyde condensation and the like.
4. Safety Information:
- DMHP is safe for human health under normal conditions, but it still needs to be handled with caution. If contact with skin or eyes is avoided, use protective gloves and goggles.
-It may decompose under high temperature, high pressure or strong oxidant conditions to produce harmful substances, so these conditions should be avoided when handling.
-When storing, keep DMHP in a dry, cool place and avoid contact with oxygen, organic solvents or other flammable substances.
1. nature:
- DMHP is a solid, usually in the form of white crystals or crystalline powder.
-It is soluble in many organic solvents at room temperature, such as ethanol, ether and dichloromethane.
- DMHP is stable in air, but may decompose under the action of high temperature, high pressure or strong oxidants.
-It is an alkaline substance that can react with acid to generate the corresponding salt.
2. use:
- DMHP is often used as a catalyst in organic synthesis reactions, especially in the synthesis of carbonyl compounds.
-It can be used as a condensing agent for the synthesis of aromatic aldehydes and ketones.
- DMHP can also be used to synthesize biologically active compounds, such as drugs and natural products.
3. Preparation method:
The synthesis of-DMHP is usually achieved by introducing methyl and hydroxyl groups at the 2 and 6 positions of pyridine. Specific methods include oxidation, alkylation, aldehyde condensation and the like.
4. Safety Information:
- DMHP is safe for human health under normal conditions, but it still needs to be handled with caution. If contact with skin or eyes is avoided, use protective gloves and goggles.
-It may decompose under high temperature, high pressure or strong oxidant conditions to produce harmful substances, so these conditions should be avoided when handling.
-When storing, keep DMHP in a dry, cool place and avoid contact with oxygen, organic solvents or other flammable substances.
Last Update：2024-04-09 20:49:11
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